THE RESULTS OF PENETRATING KERATOPLASTY FOR KERATOCONUS

  • Vesna Morela Očesni oddelek Splošna bolnišnica Novo mesto Šmihelska cesta 1 8000 Novo mesto
  • Kristina Mikek Očesna klinika Klinični center Zaloška 29 1525 Ljubljana
Keywords: penetrating keratoplasty, keratoconus, visual acuity, postoperative astigmatism, other postoperative complications

Abstract

Background. To evaluate etiology, indications, results and complication rates associated with corneal transplantation for keratoconus.

Methods. In this retrospective clinical study, 101 eyes of 79 patients had corneal transplantation. Mean age at surgery was 30.5 years. Follow up period was 2 to 25 yrs. All surgeries were performed by one surgeon. Candidate for surgery were patients who cannot tolerate contact lenses or are not adequately visually rehabilitated by them. Before surgery the best corrected visual acuity was 0.05 to 0.3 in 27%; 73% of patients had uncorrected visual acuity hand movement or counting fingers.

Results. Best corrected visual acuity postoperatively was in 72% of patients 0.5 to 1.0and in 26% 0.4 to 0.1. 2% of patients had visual acuity less than 0.1. In all cases we had postkeratoplasty astigmatism of 2.5 ± 4.75Cyl with or without residual myopia. The most often postoperative complication was graft rejection (10%) which was successfully treated with medications. Unsuccessfull rate was 3%.

Conclusions. The improved results, low complication rate, and postoperative enhancement management indicate that corneal transplantation is a viable option in the clinical course of keratoconus. The optimal visual acuity postoperatively is achieved with contact lens, which correct postoperative astigmatism and myopia. Improvements in refractive surgery can help manage with postkeratoplasty astigmatism and myopia.

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References

Rabinowitz YS. Keratoconus. Survey of Ophthalmology 1998; 42: 297–319.

Cursiefen C, Küchle M, Naumann GOH. Changing indications for penetrating keratoplasty: histopathology of 1250 corneal buttons. Cornea 1998; 17 (5): 468–70.

Gračner B, Pahor D. Transplantacije roženic na Oddelku za očesne bolezni v Mariboru, 1984–1998. In: Zbornik predavanj in praktikum simpozija Transplantacija, sodoben način zdravljenja. Splošna bolnišnica Maribor, 1998: 173–8.

Mortensen J, Ohrstrom A. Eximer laser photorefractive keratectomy for treatment of keratoconus. J Refract Corneal Surg 1994; 10: 368–72.

Shows TB, Sakaguchi AY, Naylor SL. Mapping the human genome, cloned genes, DNA polymorphisms, and inherited disease. Adv Hum Genet 1982; 12: 341–468.

Tuft SJ, Moodaley LC, Gregory WM et al. Prognostic factors of progression to keratoconus. Ophthalmology 1994; 101: 439–47.

Tuft SJ, Fitzke FW, Buckley RJ. Myopia following penetrating keratoplasty for keratoconus. Ophthalmology 1992; 76: 642–5.

Tuft SJ, Gregory WM, Davison CR. Bilateral penetrating keratoplasty for keratoconus. Ophthalmology 1995; 102: 462–8.

Wang MX, Karp CL, Selkin RP, Azar DT. Corneal and conjunctival surgery. In: Yanoff M, Duker JS eds. Ophthalmology 1st ed. London: Mosby, 1999: 5.12.118.

Girard LJ, Esnaola N, Rao R, Barnett L, El Maghraby A, Canizales R. Allograft rejection after penetrating keratoplasty for keratoconus. Ophthalmic Surg 1993; 24 (1): 40–3.

Webber SK, Lawless MA, Sutton GL, Rogers CM. LASIK for postpenetrating keratoplasty astigmatism and myopia. Br J Ophthalmol 1999; 83: 1013–8.

Buzard KA, Fundingsland BR. Corneal transplant for keratoconus: results in early and late disease. J Cataract Refract Surg 1997; 23: 398–406.

Koralewska-Makar A, Floren I, Stenevi U. The results of penetrating keratoplasty for keratoconus. Acta Ophthalmol Scand 1996; 74: 187–90.

Ehlers N, Olsen T. Long term results of corneal grafting in keratoconus. Acta Ophthalmol 1983; 61: 918–26.

Yorston D, Wood M, Foster A. Penetrating keratoplasty in Africa: graft survival and visual outcome. Br J Ophthalmol 1996; 80: 890–4.

Brierly SC, Izquierdo L, Mannis MJ. Penetrating keratoplasty for keratoconus. Cornea 2000; 19 (3): 329–32.

Sharif KW, Casey TA. Penetrating keratoplasty for keratoconus: complications and long-term success. Br J Ophthalmol 1991; 75: 142–6.

Levenson JE. Corneal transplantation: early postoperative management. In: Brightbill FS ed. Corneal surgery, theory, technique, tissue. 3rd ed. New York: Mosby, 1999: 364–79.

Pfeifer V, Schwarzbartl-Grošelj MA. Perforativna keratoplastika. Zdrav Vestn 1996; 65: 277–80.

How to Cite
1.
Morela V, Mikek K. THE RESULTS OF PENETRATING KERATOPLASTY FOR KERATOCONUS. TEST ZdravVestn [Internet]. 1 [cited 5Aug.2024];71. Available from: http://vestnik-dev.szd.si/index.php/ZdravVest/article/view/1716
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Professional Article

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