4-YEAR FOLLOW UP OF PATIENTS AFTER GONIOTREPANATION
Abstract
Background. To present the success of goniotrepanation in patients with glaucoma 4 years after surgery.
Methods. We performed follow-up of 32 patients (50 eyes), who had undergone Fronimopoulus goniotrepanation without use of antimetabolites in our department because of poorly controlled primary open-angle or angle-closure glaucoma and pseudoexfoliative glaucoma between January 1995 and May 1996. The success of operation was assessed 4 years after operation by evaluating the stability of the visual field, stability of the optic nerve head changes and values of the intraocular pressure (IOP) lower than 21 mm Hg.
Results. Mean preoperative IOP was 27 mm Hg, one year postoperatively 15 mm Hg and 4 years after the surgery 14 mm Hg (mean drop of IOP was 48%). 1 year after surgery IOP was lower than 21 mm Hg without treatment in 37 eyes (74%) and with additional topical treatment in 12 eyes (24%). After 4 years additional topical treatment was necessary in 54% eyes. Only in 2 patients (4%) revision soon after surgery was performed (because of Tenon’s cyst in one case and hypotony in the other). In 1 eye (2%) intraoperative subhoroidal expulsive hemorrhage occurred. In 19 eyes (39%) cataract developed 4 years after surgery. The success of surgery after 4 years was 94%; in 22 eyes (44%) without treatment, in 25 eyes (50%) with additional topical treatment and in 2 eyes (4%) additional surgery was needed.
Conclusions. Goniotrepanation without use of antimetabolites can be effective treatment for patients with pseudoexfoliative glaucoma and open-angle glaucoma.
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References
American Academy of Ophthalmology. Glaucoma. San Francisco: American Academy of Ophthalmology, 1998-99: 114–27.
Cairns JE. Trabeculectomy: preliminary report of a new method. Am J Ophthalmol 1968: 90: 673–9.
Picht G, Grehn F. Sicherkissenentwicklung nach Trabekulektomie. Ophthalmologie 1998; 95: 380–7.
Kurelac Z, Gračner B. Das Verhältnis zwischen der Größe des Sicherkissens und dem intraokularen Druck nach Goniotrepanation. Klin Monatsbl Augenheilkd 1987; 190: 461–1.
Khalili MA, Diestelhorst M, Kriegelstein GK. Langzeituntersuchung von 700 Trabekulektomien. Klin Monatsbl Augenheilkd 2000; 217: 1–8.
Greve EL, Dake CL, Klaver JH, Mutsaerts EM. Ten year prospective follow-up of a glaucoma operation. The Double Flap Scheie in primary open angle glaucoma. Int Ophthalmol 1985; 8 (3): 139–46.
Bayer AU, Erb C, Ferrari F, Knorr M, Thiel HJ. The Tübingen glaucoma study. Ger J Ophthalmol 1995; 4: 289–93.
Mills KB. Trabeculectomy: a retrospective long-term follow-up of 444 cases. Br J Ophthalmol 1981; 65: 790–5.
Mietz H, Raschka B, Kriegelstein GK. Risk factors for failures of trabecul-ectomies performed without antimetabolites. Br J Ophthalmol 1999; 83: 814–21.
Yamamoto T, Varani J, Soong HK, Lichter PR. Effect of 5-fluorouracil and mitomycin C on cultured rabbit subconjunctival fibroblasts. Ophthalmology 1990; 97: 1202–10.
Jacobi PC, Dietlein TS, Kriegelstein GK. Adjunctive mitomycin C in primary trabeculectomy in young adults: a long-term study of case-matched young patients. Graefes Arch Clin Exp Ophthalmol 1998; 236 (9): 652–7.
Costa VP, Moster MR, Wilson RP, Schmidt CM, Gandham S, Smith M. Effects of topical mitomycin C on primary trabeculectomies and combined procedures. Br J Ophthalmol 1993; 77: 693–7.
Smith MF, Sherwood MB, Doyle JW, Khaw PT. Results of intraoperative 5-fluorouracil supplementation on trabeculectomy for open-angle glaucoma. Am J Ophthalmol 1992; 114: 737–41.
Goldenfeld M, Krupin T, Ruderman JM et al. 5-fluorouracil in initial trabeculectomy. Ophthalmology 1994; 101: 1024–9.
The Fluorouracil Filtering Surgery Study Group. Five-year Follow-up of the Fluorouracil Filtering Surgery Study. Am J Ophthalmol 1996; 121: 349–66.
Patitsas CJ, Rockwood EJ, Meisler DM et al. Glaucoma filtering surgery with postoperative 5-fluorouracil in patients with intraocular inflammatory disease. Ophthalmology 1992; 99: 594–9.
Tsai JC, Feuer WJ, Parrish IIRK et al. 5-fluorouracil filtering surgery and neovascular glaucoma. Ophthalmology 1995; 102: 887–93.
Zacharia PT, Deppermann SR, Schuman JS. Ocular hypotony after trabeculectomy with mitomycin C. Am J Ophthalmol 1993; 116: 314–26.
Wolner B, Leibmann JM, Sassani JW, Ritch R, Speaker M, Marmor M. Late bleb-related endophthalmitis after trabeculectomy with adjunctive 5-fluorouracil. Ophthalmology 1991; 98: 1053–60.
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