MANAGEMENT OF CERVICAL LYMPH NODES IN PATIENTS WITH LARYNGEAL CARCINOMA – PATTERNS OF FAILURE

  • Aleksandar Aničin University Department of Otorhinolaryngology and Cervicofacial Surgery Clinical Center Zaloška 2 1525 Ljubljana
  • Miha Žargi University Department of Otorhinolaryngology and Cervicofacial Surgery Clinical Center Zaloška 2 1525 Ljubljana
Keywords: neck dissection, selective, laryngeal squamous cell carcinoma

Abstract

The purpose of our study was to show the patterns of regional failure when a neck dissection is chosen as part of a laryngeal cancer operation, focusing our interest on selective neck dissections. From January 1, 1987 through December 31, 1991, we performed 374 neck dissections on 207 previously untreated patients with laryngeal squamous cell carcinoma. Selective neck dissections represented the majority of all dissections performed (87%). The overall regional recurrence rate was 4.84% and the average duration of follow-up 58 months after operation. The regional in-field recurrence rate after selective neck dissections in postoperatively irradiated N2b and N1 cases was 12.5% and 8.3%, respectively. It seems that a more comprehensive neck dissection would not benefit these patients, because the majority of regional recurrences developed in the dissected field. Selective neck dissections with postoperative radiotherapy represent appropriate therapeutic and not only diagnostic procedures in the treatment of patients with laryngeal carcinoma, even in N2b cases.

Downloads

Download data is not yet available.

References

Spiro RH, Alfonso AE, Farr HV, Strong EW. Cervical node metastases from epidermoid carcinoma of the oral cavity and oropharynx. A critical assessment of current staging. Am J Surg 1974; 128: 562–7.

Lindberg RD. Distribution of cervical lymph node metastases for squamous cell carcinoma of the upper respiratory tract. Cancer 1972; 29: 1446–9.

Mc Gavran MH, Bauer WC, Ogura JH. The incidence of cervical lymph node metastases from epidermoid carcinoma of the larynx and their relationship to certain characteristics of the primary tumour. Cancer 1961; 14: 55–66.

Kambič V, Plesničar S. Vrednotenje limfadenopatij na vratu. Zdrav Vestn 1962; 31: 276–84.

Ogura JH, Biller HF. Cysts and tumours of the larynx. In: Paparella MM, Schumrick DA: Otolaryngology (Head and neck – Vol III). PhiladelphiaLondon-Toronto: WB Saunders, 1973: 658–81.

Ogura JH, Biller HF, Wette R. Elective neck dissection for pharyngeal and laryngeal cancers: an evaluation. Ann Otol Rhinol Laryngol 1971; 80: 646–51.

Lee JG, Krause CJ. Radical neck dissection. Elective, therapeutic and secondary. Arch Otolaryngol 1975; 101: 656–9.

Ali S, Tiwari RM, Snow GB. False positive and false negative neck nodes. Head Neck Surg 1985; 8: 78–82.

Friedman M, Shelton VK, Mafee M, Bellity P, Grybauskas V, Skolnik E. Metastatic neck disease: evaluation by computed tomography. Arch Otolaryngol 1984; 110: 443–7.

Brekel MWM, van den, Stel HV, Castelijns JA, Nauta JJ, Waal I van der, Valk J , Meyer CJ, Snow GB. Cervical lymph node metastases: assessment of radiologic criteria. Radiology 1990; 177: 379–84.

Brekel MWM van den, Castelijns JA, Stel HV, Luth WJ, Valk J, Waal I van der, Snow GB. Occult metastatic neck disease: detection with ultrasound and ultrasound-guided fine needle aspiration cytology. Radiology 1991; 180: 457–61.

Višnar-Perovič A, Aničin A, Zupančič Ž, Černelč B, Šmid L, Vidmar DB, Gorenc M. Ultrasound-guided aspiration biopsy of subclinical regional metastases of head and neck carcinoma. Radiol Oncol 2000; 34 (2): 115–22.

Takashima S, Sone S, Nomura N, Tomiyama N, Kobayashi T, Nakamura H. Nonpalpable lymph nodes of the neck: assessment with US and US-guided fine-needle aspiration biopsy. J Clin Ultrasound 1997; 25: 283–92.

Brekel MWM van den, Castelijns JA, Snow GB. Diagnostic evaluation of the neck. Otolaryngol Clin North Am 1998; 31: 601–20.

Leemans CR, Tiwari R, Nauta JJP, van der Waal I, Snow GB. Regional lymph node involvement and its significance in the development of distant metastases in head and neck carcinoma. Cancer 1993; 71: 452–6.

Byers RM, Wolf PF, Ballantyne AJ. Rationale for elective modified neck dissection. Head Neck 1988; 10: 160–7.

Myers EN, Fagan JJ. Management of the neck in the cancer of the larynx. Ann Otol Rhinol Laryngol 1999; 108: 828–32.

Žargi M. Funkcionalna disekcija vratu. Zbornik predavanj s kongresa otorinolaringologov Jugoslavije. Priština: Združenje otorinolaringologov Jugoslavije, 1987: 120–5.

Byers RM, Clayman GL, McGill D, Andrews T, Kare RP, Roberts DB, Goepfert H. Selective neck dissections for squamous cell carcinoma of the upper aerodigestive tract: patterns of regional failure. Head Neck 1999; 21: 499– 505.

Shah JP. Patterns of cervical lymph node metastasis from squamous cell carcinoma of the upper aerodigestive tract. Am J Surg 1990; 160: 405–9.

Medina JE, Byers RM. Supraomohyoiod neck dissection: rationale, indications and surgical technique. Head Neck Surg 1989; 11: 111–22.

Pellitteri PK, Robbins KT, Neuman T. Expanded application of selective neck dissection with regard to nodal status. Head Neck 1997; 19: 260–5.

Johnson JT, Myers EN, Bedetti CD, Barnes EL, Schramm VL, Thearle PB. Cervical lymph node metastasis. Incidence and implications of extracapsular carcinoma. Arch Otolaryngol 1985; 111: 534–7.

How to Cite
1.
Aničin A, Žargi M. MANAGEMENT OF CERVICAL LYMPH NODES IN PATIENTS WITH LARYNGEAL CARCINOMA – PATTERNS OF FAILURE. TEST ZdravVestn [Internet]. 1 [cited 5Aug.2024];71. Available from: http://vestnik-dev.szd.si/index.php/ZdravVest/article/view/1771
Section
Original article