Creutzfeldt-jakobova bolezen in dekontaminacija prionov
Abstract
Abstract: Prion decontamination methods known so far have been described and discussed in this article. The only usable chemical is NaOCl but not effectfull in all cases and unusable for stainless steel. Best results were obtained autoclaving 1 or 0.1N NaOH simultaneously at 121–134 °C but this cannot be used for glass and aluminium. Combination of alkaline detergents and proteolytic enzymes has been successful, in some cases, but they also can be combined with autoclaving for thermostabile devices. Drying of instruments after use must be avoided under any circumstances during the transport of instruments from operation rooms to the sterilization department. This can be done without great investments. In general, in most world hospitals prion decontamination methods are not adequate. This guilt for Slovenia as well.
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References
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