APPLICATION OF THE RETINAL THICKNESS ANALYSER IN RETINAL DISEASES AND GLAUCOMA
Abstract
Background. A change in retinal thickness caused by several ocular diseases can be measured quantitatively by the retinal thickness analyser (RTA). The principle of RTA is based on projecting a laser slit (540 nm) onto the retina and viewing its intersection with the retina. The separation between the reflections from the vitreoretinal and the chorioretinal interface is a measure of the retinal thickness. By scanning the posterior pole and/or peripapillary retina, the intersections of the laser slit with the retina are presented as multiple optical cross sections and as colour-coded retinal thickness maps.
Conclusions. In the article the application of the new method in glaucoma and other retinal diseases is presented. Scanning RTA is a non-invasive method and provides quantitative information that may be useful in the diagnosis and monitoring of glaucoma and a variety of retinal diseases in clinical practice.
Downloads
References
Zeimer R, Shahidi M, Mori M, Zou S, Asrani S. A new method for rapid mapping of the retinal thickness at the posterior pole. Invest Ophthalmol Vis Sci 1996; 37: 1994–2001.
Quigley HA, Addicks EM, Green WR. Optic nerve damage in human glaucoma. Arch Ophthalmol 1982; 100: 135–46.
Curcio CA, Allen KA. Topography of ganglion cells in human retina. J Comp Neurol 1990; 300: 5–25.
Zeimer R, Asrani S, Zou S, Quigley H, Jampel H. Quantitative detection of glaucomatous damage at the posterior pole by retinal thickness mapping. Ophthalmology 1998; 105: 224–31.
Brusini P, Tosoni C, Miani F. Quantitative mapping of the retinal thickness at the posterior pole in chronic open glaucoma. Acta Ophthalmol Scand Suppl 2000; 78: 42–4.
Early Treatment Diabetic Retinopathy Study Group. Focal photocoagulation treatment of diabetic macular edema. ETDRS report 19. Arch Ophthalmol 1995; 113: 1144–55.
Oshima Y, Emi K, Yamanishi S, Motokura M. Quantitative assessment of macular thickness in normal subjects and patients with diabetic retinopthy by scanning retinal thickness analyser. Br J Ophthalmol 1999; 83: 54–61.
Pires I, Bernardes RC, Lobo CL, Soares MA, Cunha-Vaz JG. Retinal thickness in eyes with mild nonproliferative retinopathy in patients with type 2 diabetes mellitus: comparison of measurements obtained by retinal thickness analysis and optical coherence tomography. Arch Ophthalmol 2002; 120: 1301–6.
Fritsche P, van der Heide R, Suttorp-Schulten MSA, Polak BC. Retinal thickness analysis. An objective method to assess and quantify the retinal thickness in healthy controls and in diabetics without diabetic retinopathy. Retina 2002; 22: 768–71.
Asrani S, Zeimer R, Goldberg MF, Zou S. Application of rapid scanning retinal thickness analysis in retinal diseases. Ophthalmology 1997; 104: 1145– 51.
Brown GC, Shields JA, Goldberg RE. Congenital pits of the optic nerve head II. Clinical studies in humans. Ophthalmology 1980; 87: 51–65.
Rutledge BK, Puliafito CA, Duker JS, Hee MR, Cox MS. Optical coherence tomography of macular lesions associated with optic nerve head pits. Ophthalmology 1996; 103: 1047–53.
Oshima Y, Emi K. Optical cross-sectional assessment of the macula by retinal thickness analyser in optic disk pit maculopathy. Am J Ophthalmol 1999; 128: 106–9.
Todokoro D, Kishi S. Reattachment of retina in retinoschisis in pit-macular syndrome by surgically-induced vitreous detachment and gas tamponade. Ophthalmic Surg Lasers 2000; 31: 233–5.
The Author transfers to the Publisher (Zdravniški vestnik/Slovenian Medical Journal) all economic copyrights following form Article 22 of the Slovene Copyright and Related Rights Act (ZASP), including the right of reproduction, the right of distribution, the rental right, the right of public performance, the right of public transmission, the right of public communication by means of phonograms and videograms, the right of public presentation, the right of broadcasting, the right of rebroadcasting, the right of secondary broadcasting, the right of communication to the public, the right of transformation, the right of audiovisual adaptation and all other rights of the author according to ZASP.
The aforementioned rights are transferred non-exclusively, for an unlimited number of editions, for the term of the statutory
The Author can make use of his work himself or transfer subjective rights to others only after 3 months from date of first publishing in the journal Zdravniški vestnik/Slovenian Medical Journal.
The Publisher (Zdravniški vestnik/Slovenian Medical Journal) has the right to transfer the rights, acquired parties without explicit consent of the Author.
The Author consents that the Article be published under the Creative Commons BY-NC 4.0 (attribution-non-commercial) or comparable licence.
