COMPARISON OF RESULTS OF CERVICAL SMEARS vs. HISTOLOGIC RESULTS OF BIOPSY AND OF TISSUES OBTAINED DURING SURGERY
Abstract
Background: In Slovenia a national screening programme for early detection of cervical cancer (ZORA) was introduced in 2003. The efficiency of the screening programme requires an evaluation of cytology findings of cervical smears, and of the agreement between cytology findings and histologic findings of a biopsy specimen and of the tissue taken during surgery.
Methods: We collected the cytology findings of cervical smears taken at the outpatient gynecology clinic Skofja Loka in the years 2006, 2007 and 2008, and compared them to the Slovene averages, and we analyzed the histologic findings of all biopsies and of the tissue samples obtained during surgery in the same years.
Results: The findings of cervical smears are comparable to Slovene averages. Specific are a high percentage of cervical smears with atypical squamous cells and few reactive changes, which resulted in a higher percentage of repeated smears. In the 3-year period a cervical biopsy was performed in 144 women: in 111 cases (77.0 %) the result of cervical biopsy was abnormal. Histologic findings of biopsies agreed well with histologic findings of tissues taken during surgery.
Conclusions: Early detection and treatment of precancerous lesions and early forms of cervical cancer may lead to a further decrease in the incidence and mortality from cervical cancer. A con- stant analysis of our results helps us in making appropriate decisions both for a cervical biopsy and for the type of treatment.
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References
Ilijaš-KoželjM.Presejanjezarakamaterničnegavratuvočeham- bulantnega ginekologa. In: Štabuc B, ed. Rak rodil 16. seminar In memoriam dr. Dušana Reje; 2008 okt; Ljubljana. Ljubljana: Zveze slovenskih društev za boj proti raku; 2008. p. 15–25.
IncidencarakavSloveniji.Ljubljana:Ljubljana:Onkološkiinštitut. Letna poročila do 2008.
IsteničH,JemecM.Analizarezultatovbrisovmaterničnegavratu in primerjava z rezultati biopsije materničnega vratu. In: Možina A, ed. Zbornik predavanj 2. slovenski kongres o cervikalni patologiji z mednarodno udeležbo in kolposkopskim tečajem; 2007 mar 7–10; Portorož. Ljubljana: Združenje za ginekološko onkologijo, kolposkopijo in cervikalno patologijo, 2007; 104–9.
Repše-Fokter A. Skladnost citoloških in histoloških izvidov. In: Možina A, ed. Dan ginekološke onkologije: rak jajčnikov. Zbornik 1. slovenski kongres o cervikalni patologiji s kolposkopskim tečajem; 2006 mar 9–11; Kranjska Gora. Ljubljana: Združenje za ginekološko onkologijo, kolposkopijo in cervikalno patologijo, 2006; 109–11.
Register raka za Slovenijo, Poročilo za leto2006, 2007 in 2008. Ljubljana: Onkološki inštitut.
Združenjezaginekološkoonkologijo,kolposkopijoincervikalno patologijo. Smernice za celostno obravnavo žensk s predraka- vimi spremembami materničnega vratu (osnutek). Ljubljana, Združenje za ginekološko onkologijo, kolposkopijo in cervikalno patologijo;2006.
Uršič Vrščaj M, Rakar S, Možina A. Rak materničnega vratu je ob- vladljiva bolezen. In: Možina A, ed. Dan ginekološke onkologije: rak jajčnikov. Zbornik 1. slovenski kongres o cervikalni patologiji s kolposkopskim tečajem; 2006 mar 9–11; Kranjska Gora. Ljubljana: Združenje za ginekološko onkologijo, kolposkopijo in cervikalno patologijo, 2006; 51–4.
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