Ornidazole-induced fixed drug eruption: A case report
Abstract
Za fiksni medikamentozni eksantem (FDE) so značilne kožne lezije, ki se pojavijo v povezavi z določenim zdravilom. Reakcija se ponavlja na istem mestu na koži ali sluznici. Prikazan je primer 26-letne bolnice, ki smo jo sprejeli na naš urgentni oddelek zaradi močno izraženih srbečih kožnih lezij po aplikaciji ornidazola. Fizični pregled je pokazal eritematozne, hiperpigmentirane, luskaste in dobro razmejene plake brez mehurjev. V preteklosti je že imela podobno izkušnjo z uporabo ornidazola. Opravljen je bil histopatološki pregled z biopsijo. Po ukinitvi ornidazola in uvedbi lokalne in sistemske terapije z antihistaminiki in steroidnimi zdravili je pri bolnici prišlo do postopnega zmanjšanja kožnih lezij in znakov vnetja. Zaključujemo, da je pomembno, da zdravnik podrobno preuči bolnikovo anamnezo. Škodljivo zdravilo je treba opustiti in bolnika obvestiti o škodljivosti zdravila.Downloads
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