Botulizem pri dojenčku

Anja Radšel; Štefan Grosek; Anamarija Meglič; Damjan Osredkar; Alenka Andlovic

Anja Radšel Pediatrična klinika UKC Ljubljana Ljubljana
Štefan Grosek Kirurška klinika Klinični oddelek za otroško kirurgijo in intenzivno terapijo UKC Ljubljana Ljubljana
Anamarija Meglič Inštitut za mikrobiologijo in imunologijo Medicinska fakulteta Ljubljana
Damjan Osredkar Pediatrična klinika Klinični oddelek za otroško, mladostniško in razvojno nevrologijo UKC Ljubljana Bohoričeva 20 1525 Ljubljana
Alenka Andlovic Inštitut za mikrobiologijo in imunologijo Medicinska fakulteta Ljubljana

Keywords: Clostridium botulinum, infant botulism, botulinum toxin, acute infant hypotonia, constipation

Abstract

Infant botulism is a potentially fatal disease, caused by neurotoxigenic strain of Clostridium botulinum that colonizes infant’s gut. The incidence of the disease is low, but is probably underestimated in Europe. Every child with progressive hypotonia, constipation and feeding difficulties, but normal alertness, should be considered as a possible case of infant botulism. Besides a typical clinical picture, positive microbiological tests are needed to confirm the diagnosis. The specific botulinum toxin antibodies are available for treatment, but they are used only in the most severe cases. We present the first diagnosed case of infant botulism in Slovenia.

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