MULTIPLE PREGNANCY IN THE TWENTY YEARS OF IVF/ET IN SLOVENIA

  • Tomaž Tomaževič Klinični oddelek za reprodukcijo Ginekološka klinika Klinični center Šlajmerjeva 3 1525 Ljubljana
  • Irma Virant Klun Klinični oddelek za reprodukcijo Ginekološka klinika Klinični center Šlajmerjeva 3 1525 Ljubljana
  • Brigita Valentinčič Gruden Klinični oddelek za reprodukcijo Ginekološka klinika Klinični center Šlajmerjeva 3 1525 Ljubljana
  • Helena Meden Vrtovec Klinični oddelek za reprodukcijo Ginekološka klinika Klinični center Šlajmerjeva 3 1525 Ljubljana
  • Veljko Vlaisavljević Oddelek za reproduktivno medicino in ginekološko endokrinologijo Služba za ginekologijo Splošna bolnišnica Maribor Ljubljanska 5 2000 Maribor
  • Borut Kovačič Oddelek za reproduktivno medicino in ginekološko endokrinologijo Služba za ginekologijo Splošna bolnišnica Maribor Ljubljanska 5 2000 Maribor
  • Primož Reš Bolnišnica za ginekologijo in porodništvo Prečna 4 6230 Postojna
  • Ivan Verdenik Klinični oddelek za reprodukcijo Ginekološka klinika Klinični center Šlajmerjeva 3 1525 Ljubljana
Keywords: multiple pregnancy, IVF/ICSI, elective transfer of 2 blastocysts

Abstract

Background. Slovene data on iatrogenic multiple pregnancy after IVF/ICSI procedures are presented. The influence of elective transfer of two high-quality embryos on the incidence of iatrogenic multiple pregnancy were evaluated.

Methods. Retrospective analysis of the Slovene IVF/ICSI data in the period 1983–2000.

Results. In 17436 IVF/ICSI cycles 3068 pregnancies were achieved. Of the 2308 deliveries 369 (16%) were twins and 49 (2%) triplets. Of the 2827 newborns 738 (26%) were twins and 148 (5%) triplets. With elective transfer of two high quality embryos in 1999 and 2000 in two of the three Slovene centres for assisted reproduction, the pregnancy rate per transfer increased (32%), triplet deliveries decreased to 2/492 deliveries (0.4%) (p < 0.000), and twin deliveries remained unchanged 111/492 deliveries (23%).

Conclusions. After elective transfer of two high-quality embryos and cryopreservation of surplus high-quality embryos in two of the three Slovene centres in the years 1999 and 2000, the problem of iatrogenic triple and higher rate multiple pregnancies has been successfully resolved, but the twin delivery rate still remains too high. Only by elective transfer of a single high-quality embryo the high multiple pregnancy rate after IVF/ICSI procedures could be avoided.

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How to Cite
1.
Tomaževič T, Virant Klun I, Valentinčič Gruden B, Meden Vrtovec H, Vlaisavljević V, Kovačič B, Reš P, Verdenik I. MULTIPLE PREGNANCY IN THE TWENTY YEARS OF IVF/ET IN SLOVENIA. TEST ZdravVestn [Internet]. 1 [cited 5Aug.2024];72. Available from: http://vestnik-dev.szd.si/index.php/ZdravVest/article/view/2207
Issue
Vol 72 (2003): Supplement II
Section
Professional Article


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