MULTIPLE PREGNANCIES AFTER INTRACYTOPLASMIC SPERM INJECTION (ICSI)

  • Branko Zorn Klinični oddelek za reprodukcijo Ginekološka klinika Klinični center Šlajmerjeva 3 1525 Ljubljana
  • Irma Virant Klun Klinični oddelek za reprodukcijo Ginekološka klinika Klinični center Šlajmerjeva 3 1525 Ljubljana
  • Sašo Drobnič Klinični oddelek za reprodukcijo Ginekološka klinika Klinični center Šlajmerjeva 3 1525 Ljubljana
  • Tomaž Tomaževič Klinični oddelek za reprodukcijo Ginekološka klinika Klinični center Šlajmerjeva 3 1525 Ljubljana
  • Helena Meden Vrtovec Klinični oddelek za reprodukcijo Ginekološka klinika Klinični center Šlajmerjeva 3 1525 Ljubljana
Keywords: intracytoplasmic sperm injection, twinning pregnancy, monozygotic twinning, blastocyst, blastocyst freezingthawing

Abstract

Background. Because of complications related to multiple pregnancies after in vitro fertilization this pathology represent a real problem. Intracytoplasmic sperm injection (ICSI) may lead to higher risk in developing monozygotic pregnancies. We sought to investigate whether the multiple pregnancies after ICSI differ of those consecutive to classical in vitro fertilization (IVF) and if counseling for transfering one or at most two embryos is efficient in preventing multiple pregnancies.

Methods. We analyzed retrospectively data concerning the incidence of multiple pregnancies before and after the transfer of limited number of embryos.

Results. In transfering two cleaving-stage embryos (day 2) or blastocysts (day 5), when pregnancy rate is high, the incidence of multiple pregnancies is 25 and 17%. After transfer of one blastocyst the highest the pregnancy rate and the lowest the incidence of multiple pregnancies.

Conclusions. The best way to avoid multiple pregnancies consist in transferring one or at most two embryos. The monozygotic twin pregnancy we observed was consecutive to the transfer of frozen-thawed blastocyst.

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References

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How to Cite
1.
Zorn B, Virant Klun I, Drobnič S, Tomaževič T, Meden Vrtovec H. MULTIPLE PREGNANCIES AFTER INTRACYTOPLASMIC SPERM INJECTION (ICSI). TEST ZdravVestn [Internet]. 1 [cited 5Aug.2024];72. Available from: http://vestnik-dev.szd.si/index.php/ZdravVest/article/view/2212
Issue
Vol 72 (2003): Supplement II
Section
Professional Article


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