Clinical guidelines for thrombophilia testing in patients with venous thromboembolism

  • Alenka Mavri
  • Tjaša Vižintin Cuderman
  • Monika Štalc
  • Mojca Božič
  • Gregor Tratar
  • Mirjam Gubenšek
  • Anja Boc
  • Marko Miklič
  • Nina Vene

Abstract

Thrombophilia is a condition that increases susceptibility for the development of venous thromboembolism due to accelerated blood clotting. The article describes congenital and acquired thrombophilic conditions, their prevalence, the risk for a first and recurrent venous thromboembolism, and laboratory methods for the determination and evaluation of thrombophilias. Thrombophilia testing has only limited purpose and may be useful in patients with venous thromboembolism only when the results influ ence the duration of anticoagulant treatment or measures to prevent a recurrence of the disease. Therefore, thrombophilia testing includes clinically the most important thrombophilias and is recommended only in women of childbearing potential, in patients younger than 50 years with idiopathic venous thrombosis at an unusual site or suspected antiphospholipid syndrome and in patients with recurrence of idiopathic venous thromboembolism before the age of 50 years. Thrombophilia testing in other patients with venous thromboembolism cannot be justified.

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Published
2013-02-01
How to Cite
1.
Mavri A, Vižintin Cuderman T, Štalc M, Božič M, Tratar G, Gubenšek M, Boc A, Miklič M, Vene N. Clinical guidelines for thrombophilia testing in patients with venous thromboembolism. TEST ZdravVestn [Internet]. 1Feb.2013 [cited 16May2024];82(2). Available from: http://vestnik-dev.szd.si/index.php/ZdravVest/article/view/625
Issue
Vol 82 No 2 (2013): February 2013
Section
Quality and safety


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